Research in the Fangue lab is focused on understanding the physiological specializations that allow animals to survive and thrive in complex environments. Using a combination of field- and laboratory-based studies, much of our research to date has centered on understanding how variation in the abiotic parameters (e.g. oxygen, temperature) of the natural environment translates into an animal’s physiological performance. We study a variety of fish species, often those living in naturally extreme or anthropogenically-challenging habitats, to understand whether these organisms have sufficient physiological capacity or plasticity to maintain successful performance in the face of anthropogenic environmental perturbations such as climate change. The common goal in all of this work is to understand the environmental and physiological requirements of fishes at the mechanistic level (using molecular, cellular and whole-organism measures of physiological performance) in order to elucidate the connections between environment, physiology, and ecosystem function. A second important goal is to offer insight and provide recommendations to resource managers in support of fish conservation.